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	Provedor de dados BJID (2) Autor Carvalho,Edgar M. (2) Andrade,Rosana (1) Barroso Jr,Ubirajara (1) Carneiro Neto,Jose Abraão (1) Guerreiro,Jaqueline B. (1) Ho,John L. (1) Lacerda,Lino (1) Melo,Cláudio Galeno de (1) Oliveira,Cassius José (1) Orge,Gloria Orge (1) Passos,Lucia (1) Porto,Maria Aurélia F. (1) Santos,Silvane B. (1) Santos,Silvane Braga (1) Tanajura,Davi (1) Mais... Palavra-chave HTLV-1 (2) IFN-gamma (1) LPS (1) Neutrophil activation (1) Onabotulinum toxin (1) Overactive bladder (1) TNF-alpha (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2018 (1) 2005 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Onabotulinumtoxin type A improves lower urinary tract symptoms and quality of life in patients with human T cell lymphotropic virus type 1 associated overactive bladder BJID Carneiro Neto,Jose Abraão; Santos,Silvane Braga; Orge,Gloria Orge; Tanajura,Davi; Passos,Lucia; Oliveira,Cassius José; Andrade,Rosana; Melo,Cláudio Galeno de; Barroso Jr,Ubirajara; Carvalho,Edgar M.. ABSTRACT Aim: To evaluate the efficacy of the onabotulinum toxin type A in the treatment of HTLV-1 associated overactive bladder and its impact on quality of life (QoL). Methods: Case series with 10 patients with overactive bladder refractory to conservative treatment with anticholinergic or physical therapy. They received 200Ui of onabotulinumtoxin type A intravesically and were evaluated by overactive bladder symptoms score (OABSS) and King's Health Questionnaire. Results: The mean (SD) of the age was 52 + 14.5 years and 60% were female. All of them had confirmed detrusor overactivity on urodynamic study. Seven patients had HAM/TSP. The median and range of the OABSS was 13 (12–15) before therapy and decreased to 1.0 (0–12) on day 30 and to 03 (0–14)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Overactive bladder; Onabotulinum toxin; HTLV-1. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000200079 Spontaneous neutrophil activation in HTLV-1 infected patients BJID Guerreiro,Jaqueline B.; Porto,Maria Aurélia F.; Santos,Silvane B.; Lacerda,Lino; Ho,John L.; Carvalho,Edgar M.. Human T cell lymphotropic Virus type-1 (HTLV-1) induces lymphocyte activation and proliferation, but little is known about the innate immune response due to HTLV-1 infection. We evaluated the percentage of neutrophils that metabolize Nitroblue tetrazolium (NBT) to formazan in HTLV-1 infected subjects and the association between neutrophil activation and IFN-gamma and TNF-alpha levels. Blood was collected from 35 HTLV-1 carriers, from 8 patients with HAM/TSP (HTLV-1- associated myelopathy); 22 healthy individuals were evaluated for spontaneous and lipopolysaccharide (LPS)-stimulated neutrophil activity (reduction of NBT to formazan). The production of IFN-gamma and TNF-alpha by unstimulated mononuclear cells was determined by ELISA. Spontaneous NBT levels,... Tipo: Info:eu-repo/semantics/article Palavras-chave: HTLV-1; IFN-gamma; TNF-alpha; LPS; Neutrophil activation. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000600010 Registros recuperados: 2 Primeira ... 1 ... Última

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